Santiago do Cacém is a municipality in Portugal, in Setúbal district, in the Lisbon area. At the 2021 census it had 27,801 inhabitants over an area of 1,059.8 km².
Population density is about 26 per km²: a mainly rural municipality, with a main town and several villages scattered across its territory. Of the 13 municipalities in Setúbal district, it is number 9 by population.
As the crow flies it lies about 73 km south-east of Setúbal, the capital. The nearest major city is Évora, about 85 km away.
Nearby, within a few dozen kilometres, are other destinations featured in our guides: Sines (32 km), Vila Nova de Milfontes and Zambujeira (34 km).
Below you will find a map of neighbouring municipalities, the weather, places to stay in the area and a link to all the municipalities in Setúbal district.